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Some people may be allergic to exercise

This really exists.

One Wednesday two years ago Joe O'Laery went on a pizza with his parents. It was a big tomato and pizza pizza, Joe shared it with her mother. After that dinner he went to the gym. After half an hour of exercise, he began to feel strange. His eyes began to shrink and they were swollen, unable to breathe, and his face swelled.

He ended up in a hospital where he was treated with steroids and antihistamines. It was a strong allergic reaction, but not just the food it consumed. It was a combination of food and exercise. His condition is diagnosed by exercise induced anaphylaxis in which the reaction to an allergen occurs only when exercise.

The young man had an anaphylactic reaction to pheromones, tomatoes, soy and nuts. Exercise induced anaphylaxis was first described in 1979 and is likely to affect 50 out of 100,000 people. "Doctors still do not know why such an allergic reaction occurs," says Maria Castells, an allergist from Birgham and Women's Hospital in Massachusetts.

With 30 to 50 percent of people responding because of a combination of specific food and exercise. Some women do this at a certain time of the menstrual cycle when their estrogen levels are high because the hormone can bind to cells that are associated with an allergic reaction.

Castells argues that there are a lot of things that might be the cause, and sometimes it's just a mere exercise. The amount of exercise that is required to trigger an allergic reaction varies from person to person. Generally, those in good shape need more exercise. Almost all kinds of exercises, dancing, running or cycling can cause anaphylaxis. Swimming is, of course, safe, because no reaction after this activity has ever been recorded.

It is not known exactly what causes the relationship between exercise and anaphylaxis. There are theories that the mechanisms involved in and that are related to the changes that occur in exercise. Increased blood flow could exacerbate immune cells by the body.

Certain protein in the intestines also change behavior during exercise, coming into contact with food in a manner that could cause an allergic reaction. Given that exercise increases absorption in the gastrointestinal tract, it is more likely that more allergens can arrive during exercise.

All these theories are difficult to check because the condition is impossible to cause in the lab. There are no models on mice. However, the diagnosis is easy to come by. When symptoms are then recognized, they are treated like any other allergy.

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